Dimethylsulphamoyl chloride → HCID 18174605, 화합물

HRID 427596노트

반응식

HRID 427596 반응식
[C:1]([C:5]1[CH:31]=[CH:30][C:8]([C:9]([NH:11][C:12]2[CH:28]=[C:27]([NH2:29])[CH:26]=[CH:25][C:13]=2[C:14]([NH:16][C:17]2[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=2)=[O:15])=[O:10])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH3:32][N:33]([CH3:38])[S:34](Cl)(=[O:36])=[O:35]>>[C:1]([C:5]1[CH:31]=[CH:30][C:8]([C:9]([NH:11][C:12]2[CH:28]=[C:27]([NH:29][S:34]([N:33]([CH3:38])[CH3:32])(=[O:36])=[O:35])[CH:26]=[CH:25][C:13]=2[C:14]([NH:16][C:17]2[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[CH:19][CH:18]=2)=[O:15])=[O:10])=[CH:7][CH:6]=1)([CH3:4])([CH3:2])[CH3:3]

참가 물질

3

반응물 2

HCID 83372Dimethylsulphamoyl chlorideHCID 108118994-Amino-2-[[4-(1,1-dimethylethyl)benzoyl]amino]-N-(4-methoxyphenyl)benzamide

생성물 1

HCID 18174605HCID 18174605, 화합물수율 30%

실험 절차

Using the procedure described in Example 59, Part E, 2-(4-tert-butylbenzoylamino)-4-amino-N-(4-methoxyphenyl)benzamide (500 mg, 1.20 mmol) was reacted with dimethylaminosulfonyl chloride to yield 190 mg (30%) of title compound as an orange solid.

출처 및 근거

ORD 기록
ord-851c9fda1085433389424133d554a4ec
출처 데이터셋
uspto-grants-2001_11
특허 번호
US06313122B1

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