2-Aminothiazole → (2,6-Dimethyl-phenyl)-(6-pyridin-3-yl-imidazo[2,1-b]thiazol-5-yl)-amine

HRID 431202

반응식

HRID 431202 반응식
[NH2:1][C:2]1[S:3][CH:4]=[CH:5][N:6]=1.[CH3:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:9]=1[N+:15]#[C-:16].[N:17]1[CH:22]=[CH:21][CH:20]=[C:19]([CH:23]=O)[CH:18]=1>Cl(O)(=O)(=O)=O>[CH3:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH3:14])[C:9]=1[NH:15][C:16]1[N:6]2[C:2]([S:3][CH:4]=[CH:5]2)=[N:1][C:23]=1[C:19]1[CH:18]=[N:17][CH:22]=[CH:21][CH:20]=1

참가 물질

5

반응물 3

HCID 21552-AminothiazoleHCID 103713-PyridinecarboxaldehydeHCID 760092,6-Dimethylphenyl isocyanide

생성물 1

HCID 22335596(2,6-Dimethyl-phenyl)-(6-pyridin-3-yl-imidazo[2,1-b]thiazol-5-yl)-amine

시약·촉매·용매 1

HCID 24247Perchloric Acid용매

실험 절차

Compound 20 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 2-aminothiazole solution (0.1 M, MC), 0.575 ml (0.115 mmol) 2,6-dimethylphenylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 3-pyridinecarbaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w=20%) in a substance library.

출처 및 근거

ORD 기록
ord-8b21308a55324e29bc2b1a92f0de9101
출처 데이터셋
uspto-grants-2003_12
특허 번호
US06657064B2

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