Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(4-Benzyloxyphenyl)-(S)-2-ethoxypropanoic acid ethyl ester → Ethyl (2S)-2-ethoxy-3-(4-hydroxyphenyl)propanoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(4-Benzyloxyphenyl)-(S)-2-ethoxypropanoic acid ethyl ester | HCID 11099514 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | Ethyl (2S)-2-ethoxy-3-(4-hydroxyphenyl)propanoate | HCID 9816147 | 76% |
반응 단계
3-(4-Benzyloxyphenyl)-(S)-2-ethoxypropanoic acid ethyl ester was hydrogenated at atmospheric pressure for 2 hours in ethyl acetate using Pd/C as catalyst. Purification by chromatography on silica gel using toluen:ethyl acetate as eluant gave 3.83 g (yield in 3 steps 76%) of (S)-2-ethoxy-3-(4-hydroxyphenyl)propanoic acid ethyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06660879B2 |
| 출처 데이터셋 | uspto-grants-2003_12 |
| ORD ID | ord-ca88f86003e6446093eab14191cfa5ce |
| 출처 메모 | uspto-grants-2003_12 |