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HRID432078

反应详情

EQUATION

反应方程式

HRID 432078 的结构方程式

REACTANTS

反应物

1
结构：CCOC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)OCC
HCID11099514

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)[C@H](Cc1ccc(O)cc1)OCC
HCID9816147

Ethyl (2S)-2-ethoxy-3-(4-hydroxyphenyl)propanoate

C13H18O4

收率 76%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

3-(4-Benzyloxyphenyl)-(S)-2-ethoxypropanoic acid ethyl ester was hydrogenated at atmospheric pressure for 2 hours in ethyl acetate using Pd/C as catalyst. Purification by chromatography on silica gel using toluen:ethyl acetate as eluant gave 3.83 g (yield in 3 steps 76%) of (S)-2-ethoxy-3-(4-hydroxyphenyl)propanoic acid ethyl ester.

WORKUP

后处理

  1. customPurification by chromatography on silica gel