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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 432624생성일: 2026년 10월 26일

2,5-Difluorophenol → 3,4-Bis(4-methoxyphenyl)-6-(2,5-difluorophenoxy)pyridazine

https://huagongshe.com/reaction/432624

반응식

참여 물질

역할이름HCID투입량
반응물2,5-DifluorophenolHCID 94952—
반응물3,4-Bis(4-methoxyphenyl)-6-chloropyridazineHCID 12568084—
생성물3,4-Bis(4-methoxyphenyl)-6-(2,5-difluorophenoxy)pyridazineHCID 10295622—

반응 단계

In a similar manner as in Example 2, 3,4-bis(4-methoxyphenyl)-6-chloropyridazine (200 mg, 0.613 mmol) and 2,5-difluorophenol were reacted as starting materials at 150° C. for 24 hours and post-treatment was then conducted, whereby the title compound was obtained as a colorless crystalline powder (235.5 mg, 91.5%). Melting point: 174.4-175.2° C. (chloroform-hexane).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06664256B1
출처 데이터셋uspto-grants-2003_12
ORD IDord-92e8f13b173646d68425a0b293925364
출처 메모uspto-grants-2003_12