Phenyl Salicylate → N-(4-fluorophenyl)-2-hydroxybenzamide

HRID 433029

반응식

[C:1]([O:10]C1C=CC=CC=1)(=O)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[F:17][C:18]1[CH:24]=[CH:23][C:21]([NH2:22])=[CH:20][CH:19]=1>>[F:17][C:18]1[CH:24]=[CH:23][C:21]([NH:22][C:1](=[O:10])[C:2]2[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=2)[OH:4])=[CH:20][CH:19]=1

참가 물질

반응물 2

HCID 8361Phenyl Salicylate

HCID 97314-Fluoroaniline

생성물 1

HCID 478809N-(4-fluorophenyl)-2-hydroxybenzamide

실험 절차

The 4′-fluoro-salicylanilide was prepared by condensing phenyl salicylate with 4-fluoroaniline then purified as described in Example 2a. The ligand mixture was then prepared from 4′-fluoro-salicylanilide and 1,1′-bi-2-naphthol using the procedure described in Example 5a. 31P NMR (121.77 MHz): several peaks between 117.1-117.7 ppm.

후처리

customthen purified
customThe ligand mixture was then prepared from 4′-fluoro-salicylanilide and 1,1′-bi-2-naphthol using the procedure

출처 및 근거

ORD 기록: ord-b56fb0b3a2a449e5a89f3518427002b0
출처 데이터셋: uspto-grants-2003_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06664427B1

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