Methyl isobutyrate → 1,1-Dimethylethyl (2R,6S)-4-({4-[1,1-dimethyl-2-(methyloxy)-2-oxoethyl]phenyl}methyl)-2,6-dimethyl-1-piperazinecarboxylate

반응식

[CH3:1][CH:2]([CH3:7])[C:3]([O:5][CH3:6])=[O:4].C1([N-]C2CCCCC2)CCCCC1.[Li+].Br[C:23]1[CH:28]=[CH:27][C:26]([CH2:29][N:30]2[CH2:35][C@H:34]([CH3:36])[N:33]([C:37]([O:39][C:40]([CH3:43])([CH3:42])[CH3:41])=[O:38])[C@H:32]([CH3:44])[CH2:31]2)=[CH:25][CH:24]=1>C1(C)C=CC=CC=1.[Pd].C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1.C(=CC(C=CC1C=CC=CC=1)=O)C1C=CC=CC=1.C(P(C(C)(C)C)C(C)(C)C)(C)(C)C>[CH3:1][C:2]([C:23]1[CH:24]=[CH:25][C:26]([CH2:29][N:30]2[CH2:35][C@H:34]([CH3:36])[N:33]([C:37]([O:39][C:40]([CH3:41])([CH3:43])[CH3:42])=[O:38])[C@H:32]([CH3:44])[CH2:31]2)=[CH:27][CH:28]=1)([CH3:7])[C:3]([O:5][CH3:6])=[O:4]