Water → 4-(Trimethylsilyl)phenol

HRID 434396

반응식

HRID 434396 반응식
[CH3:1][Si:2]([CH3:15])([CH3:14])[C:3]1[CH:13]=[CH:12][C:6]([O:7][Si](C)(C)C)=[CH:5][CH:4]=1.O>C(O)C.Cl>[CH3:1][Si:2]([CH3:15])([CH3:14])[C:3]1[CH:13]=[CH:12][C:6]([OH:7])=[CH:5][CH:4]=1

참가 물질

5

반응물 2

HCID 962WaterHCID 262890Trimethyl{4-[(trimethylsilyl)oxy]phenyl}silane

생성물 1

HCID 257324-(Trimethylsilyl)phenol수율 93.4%

시약·촉매·용매 2

HCID 313Hydrochloric Acid촉매HCID 702Ethanol용매

실험 절차

28.7 g p-trimethylsilylphenoxytrimethylsilane was dissolved in 9 ml 95 percent ethyl alcohol. One drop of concentrated hydrochloric acid and 4 ml water were added, and the mixture was shaked for 5 minutes. After standing for another 15 minutes, the mixture was washed two times with 30 ml water and separated. The organic phase was poured into a crystallizing dish; p-trimethylsilylphenol crystallized out as white needles. After drying overnight in vacuo, 18.7 g of product was obtained (mp 76 degrees Celsius).

후처리

  1. waitAfter standing for another 15 minutes
  2. washthe mixture was washed two times with 30 ml water
  3. customseparated
  4. additionThe organic phase was poured into a crystallizing dish
  5. customp-trimethylsilylphenol crystallized out as white needles
  6. customAfter drying overnight in vacuo

출처 및 근거

ORD 기록
ord-45792f8230c445798738aae519ee22a8
출처 데이터셋
uspto-grants-1983_08
특허 번호
US04396704

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