Aniline → N-phenylcarbamoyl chloride

HRID 434530

반응식

HRID 434530 반응식
[C:1]([Cl:4])(Cl)=[O:2].[NH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>C1(C)C=CC=CC=1>[C:6]1([NH:5][C:1]([Cl:4])=[O:2])[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

참가 물질

4

반응물 2

HCID 6115AnilineHCID 6371Phosgene

생성물 1

HCID 576741N-phenylcarbamoyl chloride

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

The intermediate is then reacted with a secondary amine in an aprotic solvent such as toluene at temperatures from room temperature or below up to the boiling point of the solvent. An example of this process is the reaction of phosgene with aniline to yield the intermediate N-(phenyl)carbamyl chloride which is then reacted with N-benzyl-n-butylamine to yield 1-benzyl-1-(n-butyl)-3-(phenyl)urea.

출처 및 근거

ORD 기록
ord-e87810831aea4dcca6a2fde26a49ebcc
출처 데이터셋
uspto-grants-1983_08
특허 번호
US04397868

연결된 노트

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