Hydrochloric Acid → Benzene, 1-chloro-4-(1,1-dimethylethyl)-

반응식

Cl.[C:2](Cl)([CH3:5])([CH3:4])[CH3:3].[Cl:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[C:2]([C:11]1[CH:12]=[CH:13][C:8]([Cl:7])=[CH:9][CH:10]=1)([CH3:5])([CH3:4])[CH3:3]

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 7964Chlorobenzene

HCID 10486tert-BUTYL CHLORIDE

생성물 1

HCID 77594Benzene, 1-chloro-4-(1,1-dimethylethyl)-수율 98.7%

반응 조건

온도: 30 °C

실험 절차

To 16.9 g of chlorobenzene was added 1.5 g of ferric chloride, and hydrogen chloride gas was blown into the mixture for minutes. Then, 46 g of tert-butyl chloride was added dropwise to the mixture at 30° C. over a period of 1 hour. The mixture was maintained at 30° C. for 2 hours. The reaction mixture was washed with an aqueous solution of sodium carbonate and then with water, and evaporated under reduced pressure to give 25 g of 4-tertbutylchlorobenzene (bp.: 113° C./28 mmHg).

후처리

waitwas blown into the mixture for minutes
washThe reaction mixture was washed with an aqueous solution of sodium carbonate
customwith water, and evaporated under reduced pressure

출처 및 근거

ORD 기록: ord-544dd4e94c5a45d2b5f5ee6c13c4d0f0
출처 데이터셋: uspto-grants-1983_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04397864

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