Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(Trifluoromethyl)aniline → Benzamide, 2-chloro-N-(((4-(trifluoromethyl)phenyl)amino)carbonyl)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(Trifluoromethyl)aniline | HCID 9964 | — |
| 반응물 | 2-Chlorobenzoyl isocyanate | HCID 9942311 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | Benzamide, 2-chloro-N-(((4-(trifluoromethyl)phenyl)amino)carbonyl)- | HCID 156359 | — |
반응 단계
18.7 g of 2-chlorobenzoylisocyanate were added to 150 ml of a solution of 17.7 g of 4-trifluoromethylaniline in dry acetonitrile. After stirring at room temperature for a few hours, the crystalline precipitate was sucked off, washed with successively acetonitrile, ethanol and petroleum ether and dried in air. The desired product was obtained in a yield of 29.0 g; melting point 214° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04399152 |
| 출처 데이터셋 | uspto-grants-1983_08 |
| ORD ID | ord-3da5bf644e3242919dcb62b403d6b719 |
| 출처 메모 | uspto-grants-1983_08 |