Methanol → 2-Isopropoxyimino-2-(2-aminothiazol-4-yl)acetic acid
반응식
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[N:13][O:14][CH:15]([CH3:17])[CH3:16])[C:8]([O:10]CC)=[O:9])[N:6]=1.[OH-].[Na+].CO>O1CCCC1>[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[N:13][O:14][CH:15]([CH3:17])[CH3:16])[C:8]([OH:10])=[O:9])[N:6]=1참가 물질
5
실험 절차
Ethyl 2-(2-aminothiazol-4-yl)-2-iso-propoxyiminoacetate (syn isomer, 26.8 g.), 1 N aqueous solution of sodium hydroxide (156 ml.), methanol (156 ml.) and tetrahydrofuran (100 ml.) were treated in a similar manner to that of Example D-(4) to give 2-(2-aminothiazol-4-yl)-2-iso-propoxyiminoacetic acid (syn isomer, 15.3 g.), mp. 151° C. (dec.).
출처 및 근거
- ORD 기록
- ord-f1efbbf5241149d29469b5600e9d1f51
- 출처 데이터셋
- uspto-grants-1983_08
- 특허 번호
- US04399133
반응 노트
불러오는 중…