Methanol → 2-(2-Aminothiazol-4-yl)-2-pentyloxyiminoacetic acid
반응식
[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[N:13][O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])[C:8]([O:10]CC)=[O:9])[N:6]=1.[OH-].[Na+].CO>O1CCCC1>[NH2:1][C:2]1[S:3][CH:4]=[C:5]([C:7](=[N:13][O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])[C:8]([OH:10])=[O:9])[N:6]=1참가 물질
5
실험 절차
Ethyl 2-(2-aminothiazol-4-yl)-2-pentyloxyiminoacetate (syn isomer, 28.6 g.), 2 N aqueous solution of sodium hydroxide (100.2 ml.), methanol (100 ml.) and tetrahydrofuran (100 ml.) were treated in a similar manner to that of Example F-(4) to give 2-(2-aminothiazol-4-yl)-2-pentyloxyiminoacetic acid (syn isomer, 22.4 g.), mp 176° C. (dec.).
출처 및 근거
- ORD 기록
- ord-e5113c32ad37469698aa9fff6f26fe1c
- 출처 데이터셋
- uspto-grants-1983_08
- 특허 번호
- US04399133
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