Methyl bromoacetate → 3-Bromo-2-methoxyphenoxyacetic acid methyl ester

HRID 435507노트

반응식

HRID 435507 반응식
[Br:1][C:2]1[C:3]([O:9][CH3:10])=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.Br[CH2:12][C:13]([O:15][CH3:16])=[O:14]>>[CH3:16][O:15][C:13](=[O:14])[CH2:12][O:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([Br:1])[C:3]=1[O:9][CH3:10]

참가 물질

3

반응물 2

HCID 60984Methyl bromoacetateHCID 218775343-Bromo-2-methoxyphenol

생성물 1

HCID 541832043-Bromo-2-methoxyphenoxyacetic acid methyl ester

실험 절차

The compound of Formula XVIII wherein s is zero can also be prepared by treating 3-bromo-2-methoxyphenol with methyl bromoacetate to give 3-bromo-2-methoxyphenoxyacetic acid methyl ester which is reduced to the alcohol using, e.g., diisobutylaluminum hydride with subsequent protection of the alcohol with an R12 protecting group as generally described hereinbefore.

후처리

  1. customcan also be prepared

출처 및 근거

ORD 기록
ord-992ba6eabc2d43408cdc5486d3186ed8
출처 데이터셋
uspto-grants-1983_08
특허 번호
US04401824

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