Benzylamine → HCID 12671230, 화합물
반응식
Cl[C:2]1[N:7]2[N:8]=[CH:9][N:10]=[C:6]2[N:5]=[C:4]([CH3:11])[C:3]=1[CH2:12][CH2:13]Cl.[CH2:15]([NH2:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.C(N(CC)CC)C>C(O)C>[CH2:15]([N:22]1[C:2]2[N:7]3[N:8]=[CH:9][N:10]=[C:6]3[N:5]=[C:4]([CH3:11])[C:3]=2[CH2:12][CH2:13]1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1참가 물질
5
실험 절차
A mixture of 2g of 7-chloro-6-(2-chloroethyl)-5-methyl-s-triazolo[1,5-a]pyrimidine, 0.94g of benzylamine, 3 ml of triethylamine and 20 ml of ethanol was stirred under reflux for 1 hour. The reaction mixture was then concentrated under reduced pressure and the residue was washed with water. The crystals thus obtained were recrystallized from ethanol to give 1.4g of colorless prisms of m.p. 170.5° - 172° C.
후처리
- temperatureunder reflux for 1 hour
- concentrationThe reaction mixture was then concentrated under reduced pressure
- washthe residue was washed with water
- customThe crystals thus obtained
- customwere recrystallized from ethanol
출처 및 근거
- ORD 기록
- ord-e55ff1854022439fb5b84cc4eb176cc5
- 출처 데이터셋
- uspto-grants-1977_02
- 특허 번호
- US04007189
반응 노트
불러오는 중…