Hydrochloric Acid → 1-(2-Pentylidenehydrazino)-3,4-dihydroisoquinoline
반응식
[CH:1](=O)[CH2:2][CH2:3][CH2:4][CH3:5].[NH:7]([C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12][CH2:11][N:10]=1)[NH2:8].Cl>CCOCC>[CH:1](=[N:8][NH:7][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH2:12][CH2:11][N:10]=1)[CH2:2][CH2:3][CH2:4][CH3:5]참가 물질
5
실험 절차
Valeraldehyde (5.14 g.) was added to a refluxing solution of 1-hydrazino-3,4-dihydroisoquinoline (8 g.) in ether (300 ml.). The mixture was allowed to stand (for 45 min.) at room temperature. Ethereal hydrochloric acid was added. Recrystallization of the resulting solid from ethanol-ether gave 1-(2-pentylidenehydrazino)-3,4-dihydroisoquinoline (I: X=CH3 (CH2)3, X'=Y=Y'=Z=Z'=H) hydrochloride in two crops (11.6 g. and 0.2 g., m.p. 147°-148° C.).
후처리
- custom(for 45 min.)
- customat room temperature
- customRecrystallization of the resulting solid from ethanol-ether
출처 및 근거
- ORD 기록
- ord-044fc138a3be4b3e90b4e14608d19a88
- 출처 데이터셋
- uspto-grants-1977_02
- 특허 번호
- US04009170
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