Cystamine Dihydrochloride → HCID 21453017, 화합물

HRID 436649

반응식

HRID 436649 반응식
[F:1][C:2]([F:14])([F:13])[O:3][C:4]1[CH:12]=[CH:11][C:7]([C:8](Cl)=[O:9])=[CH:6][CH:5]=1.Cl.Cl.[NH2:17][CH2:18][CH2:19][S:20][S:21][CH2:22][CH2:23][NH2:24].[OH-:25].[Na+]>C(Cl)CCl>[CH2:19]([S:20][S:21][CH2:22][CH2:23][NH:24][C:8](=[O:9])[C:7]1[CH:11]=[CH:12][C:4]([O:25][C:2]([F:1])([F:13])[F:14])=[CH:5][CH:6]=1)[CH2:18][NH:17][C:8](=[O:9])[C:7]1[CH:11]=[CH:12][C:4]([O:3][C:2]([F:14])([F:13])[F:1])=[CH:5][CH:6]=1

참가 물질

5

반응물 3

HCID 5941Cystamine DihydrochlorideHCID 14798Sodium HydroxideHCID 1421104-(Trifluoromethoxy)benzoyl Chloride

생성물 1

HCID 21453017HCID 21453017, 화합물

시약·촉매·용매 1

HCID 111,2-Dichloroethane용매

실험 절차

m.p. 150°-151° C., 14.5 g., was prepared as in Example 1 using 33.6 g. of 4-trifluoromethoxybenzoyl chloride in 100 ml. of ethylene dichloride, 11.3 g. of cystamine dihydrochloride, 300 ml. of 10% sodium hydroxide solution, 400 ml. of ethylene dichloride and recrystallization from acetonitrile using decolorizing charcoal.

후처리

  1. custom, was prepared as in Example 1 using 33.6 g
  2. customof ethylene dichloride and recrystallization from acetonitrile using

출처 및 근거

ORD 기록
ord-6f459ac2cfe64807a84e0880839d34fc
출처 데이터셋
uspto-grants-1977_02
특허 번호
US04009208

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