Hydrochloric Acid → 10-Methyl-6-oxa-9-undecene-2-one

HRID 436869노트

반응식

HRID 436869 반응식
C1CO[C:3]([CH2:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][CH:11]=[C:12]([CH3:14])[CH3:13])([CH3:4])[O:2]1.Cl>CC(C)=O>[CH3:13][C:12]([CH3:14])=[CH:11][CH2:10][CH2:9][O:8][CH2:7][CH2:6][CH2:5][C:3](=[O:2])[CH3:4]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 867348312,2-Ethylenedioxy-10-methyl-6-oxa-9-undecene

생성물 1

HCID 8673483210-Methyl-6-oxa-9-undecene-2-one수율 98.7%

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

A suspension of 19.7 g of the product of Step A in 100 ml of acetone containing 200 ml of 0.1N hydrochloric acid was stirred at room temperature for 17 hours and the acetone was then evaporated under reduced pressure. The mixture was then extracted with methylene chloride and the organic solution was washed with aqueous sodium bicarbonate solution, then with water, dried over sodium sulfate and evaporated to dryness to obtain 15.7 g of 10-methyl-6-oxa-9-undecene-2-one in the form of a colorless liquid used as is for the next step.

후처리

  1. customthe acetone was then evaporated under reduced pressure
  2. extractionThe mixture was then extracted with methylene chloride
  3. washthe organic solution was washed with aqueous sodium bicarbonate solution
  4. dry with materialwith water, dried over sodium sulfate
  5. customevaporated to dryness

출처 및 근거

ORD 기록
ord-12387d8f27c24eb89f5877ec4a9b4343
출처 데이터셋
uspto-grants-1977_06
특허 번호
US04028386

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