Ethyl formate → Hydrazinecarboxaldehyde, 2-(4-nitrophenyl)-

HRID 437282

반응식

HRID 437282 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][NH2:11])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH:12]([O-])=[O:13].[Na+].C(OCC)=O>C(O)C.C(O)=O>[CH:12]([NH:11][NH:10][C:7]1[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=1)=[O:13]

참가 물질

6

반응물 3

HCID 8025Ethyl formateHCID 2723810Sodium FormateHCID 3310889(4-Nitrophenyl)hydrazine

생성물 1

HCID 5008489Hydrazinecarboxaldehyde, 2-(4-nitrophenyl)-

시약·촉매·용매 2

HCID 284Formic Acid용매HCID 702Ethanol용매

실험 절차

4-Nitrophenylhydrazine (9.2 g, 0.06 mole), sodium formate (4.08 g, 0.06 mole), and ethyl formate (148 g, 2.00 moles) were mixed in ethanol (40 ml) and formic acid (30 ml). The mixture was heated on a steam bath; the volume of the mixture was reduced to approximately 100 ml by continued boiling. The hydrazide product crystallized out of the concentrated reaction mixture upon cooling. The product was filtered off, washed with ethanol, and dried. Yield 10.2 g (94%), m.p. 183°-185° C.

후처리

  1. temperatureThe mixture was heated on a steam bath
  2. customThe hydrazide product crystallized out of the concentrated reaction mixture
  3. temperatureupon cooling
  4. filtrationThe product was filtered off
  5. washwashed with ethanol
  6. customdried

출처 및 근거

ORD 기록
ord-4763fac989e34e39a6a0a531a6d878a6
출처 데이터셋
uspto-grants-1977_06
특허 번호
US04030925

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