HCID 54682948, 화합물 → 4-Hydroxy-5,6,7,8-tetrahydroquinolin-2(1H)-one
반응식
C([C:6]1[C:7](=[O:17])[NH:8][C:9]2[CH2:10][CH2:11][CH2:12][CH2:13][C:14]=2[C:15]=1[OH:16])(OCC)=O>Cl>[OH:16][C:15]1[C:14]2[CH2:13][CH2:12][CH2:11][CH2:10][C:9]=2[NH:8][C:7](=[O:17])[CH:6]=1참가 물질
3
실험 절차
A suspension of 3-carboethoxy-4-hydroxy-5,6,7,8-tetrahydro-carbostyril (19.4g; 0.082 mole) in 2N hydrochloric acid (200 ml) was refluxed 30 hrs. and the clear solution evaporated to dryness. Water was added and the solution brought to pH 4.0 with dilute sodium hydroxide solution. The precipitated white product was filtered off, washed well with water and recrystallised from glacial acetic acid, m.p. >330° C.
후처리
- temperaturewas refluxed 30 hrs
- customand the clear solution evaporated to dryness
- additionWater was added
- filtrationThe precipitated white product was filtered off
- washwashed well with water
- customrecrystallised from glacial acetic acid, m.p. >330° C.
출처 및 근거
- ORD 기록
- ord-ab229d0829e7406284b198965c6f9a3c
- 출처 데이터셋
- uspto-grants-1977_06
- 특허 번호
- US04031099
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