Sulfuric Acid → HCID 21429342, 화합물

HRID 437608

반응식

HRID 437608 반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[C:4]([N+:9]([O-:11])=[O:10])[CH:3]=1.[OH-].[Na+].[I-].[K+].[I:16]([O-])(=O)=O.[K+].S(=O)(=O)(O)O.S([O-])([O-])=O.[Na+].[Na+]>O.C(O)C>[F:1][C:2]1[CH:3]=[C:4]([N+:9]([O-:11])=[O:10])[C:5]([OH:8])=[C:6]([I:16])[CH:7]=1

참가 물질

9

반응물 6

HCID 1118Sulfuric AcidHCID 4875Potassium IodideHCID 14798Sodium HydroxideHCID 24437Sodium SulfiteHCID 1362364-Fluoro-2-nitrophenolHCID 23665710Potassium Iodate

생성물 1

HCID 21429342HCID 21429342, 화합물수율 176.4%

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매2회

실험 절차

A slurry of 4-fluoro-2-nitrophenol (3.3 g), sodium hydroxide (0.83 g), potassium iodide (2.33 g) and potassium iodate (1.5 g) in water (21 ml) was added to a stirred mixture of ethanol (16 ml), water (3.5 ml) and concentrated sulphuric acid (1.7 ml) at 50°. The mixture was heated under reflux for 2 hours and was then allowed to stand at room temperature overnight. A small quantity of sodium sulphite was added to decolourise the product and the yellow solid was filtered and crystallised from aqueous ethanol to give yellow crystalls of 4-fluoro-2-iodo-6-nitrophenol (3.5 g) m.p. 40°.

후처리

  1. temperatureThe mixture was heated
  2. temperatureunder reflux for 2 hours
  3. filtrationthe yellow solid was filtered
  4. customcrystallised from aqueous ethanol

출처 및 근거

ORD 기록
ord-e92430831f114d0f9fc0f4e6d18081f9
출처 데이터셋
uspto-grants-1977_06
특허 번호
US04031249

연결된 노트

불러오는 중…