Sulfuric Acid → Isopropyl acetoacetate

HRID 437726

반응식

HRID 437726 반응식
[C:1]([O:7][CH2:8][CH3:9])(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4].S(=O)(=O)(O)O.[CH:15](O)(C)C>>[C:1]([O:7][CH:8]([CH3:15])[CH3:9])(=[O:6])[CH2:2][C:3]([CH3:5])=[O:4]

참가 물질

4

반응물 3

HCID 1118Sulfuric AcidHCID 3776IsopropanolHCID 8868Ethyl Acetoacetate

생성물 1

HCID 68329Isopropyl acetoacetate

실험 절차

A solution of ethyl acetoacetate (250 g.) and concentrated sulphuric acid (10 ml.) in isopropanol (1500 ml.) was heated at reflux for 3 hours. The solvent was removed by distillation, the residue was neutralised by treatment with barium carbonate, filtered and distilled under reduced pressure to give isopropyl acetoacetate (139 g.), b.p. 79°-82° C./20 mm Hg, in the form of a colourless liquid.

후처리

  1. temperatureat reflux for 3 hours
  2. customThe solvent was removed by distillation
  3. filtrationfiltered
  4. distillationdistilled under reduced pressure

출처 및 근거

ORD 기록
ord-b6056c242bd844a3a1b4bf0f9035f329
출처 데이터셋
uspto-grants-1977_06
특허 번호
US04032323

연결된 노트

불러오는 중…