Water → 1,2,3,9-Tetrahydro-6-methoxy-9-methyl-4H-carbazol-4-one
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[C:1](=O)([O-])[O-].[K+].[K+].[CH3:7][O:8][C:9]1[CH:10]=[C:11]2[C:19](=[CH:20][CH:21]=1)[NH:18][C:17]1[CH2:16][CH2:15][CH2:14][C:13](=[O:22])[C:12]2=1.S(OC)(OC)(=O)=O.O>CC(C)=O>[CH3:7][O:8][C:9]1[CH:10]=[C:11]2[C:19](=[CH:20][CH:21]=1)[N:18]([CH3:1])[C:17]1[CH2:16][CH2:15][CH2:14][C:13](=[O:22])[C:12]2=1참가 물질
6
실험 절차
Anhydrous potassium carbonate (2.24 g) was added to a solution of the product of Stage (i) (3 g) in acetone (30 ml) at room temperature and stirred for 30 min. Dimethyl sulphate (1.6 ml) was added and the mixture was heated to reflux for 4 h. The resulting solution was poured into water (150 ml) and the resulting precipitate filtered off to give the title compound as a solid (2.5 g), m.p. 150°-151°.
후처리
- temperaturethe mixture was heated
- temperatureto reflux for 4 h
- filtrationthe resulting precipitate filtered off
출처 및 근거
- ORD 기록
- ord-1ac4895b46ac455b903ac181d0e5e30d
- 출처 데이터셋
- uspto-grants-1988_02
- 특허 번호
- US04725615
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