Acetic Anhydride → HCID 18188084, 화합물

HRID 439314

반응식

HRID 439314 반응식
[OH:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N+:11]([O-:13])=[O:12])[C:5]([OH:7])=[O:6].[C:14](OC(=O)C)(=[O:16])[CH3:15]>N1C=CC=CC=1>[C:14]([O:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[N+:11]([O-:13])=[O:12])[C:5]([OH:7])=[O:6])(=[O:16])[CH3:15]

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 692653-Hydroxy-4-nitrobenzoic acid

생성물 1

HCID 18188084HCID 18188084, 화합물

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

A mixture of 3-hydroxy-4-nitrobenzoic acid (10 g, 55 mmole) in acetic anhydride (20 ml) and anhydrous pyridine (20 ml) was refluxed for 4 hours. The reaction mixture was poured onto ice and the resulting mixture was extracted with ethyl acetate (2×100 ml). The organic layer was washed successively with dilute Hcl solution (2×100 ml) and saturated brine solution, dried over Na2SO4, filtered and evaporated to give 3-acetoxy-4-nitrobenzoic acid.

후처리

  1. temperaturewas refluxed for 4 hours
  2. additionThe reaction mixture was poured onto ice
  3. extractionthe resulting mixture was extracted with ethyl acetate (2×100 ml)
  4. washThe organic layer was washed successively
  5. additionwith dilute Hcl solution (2×100 ml) and saturated brine solution
  6. dry with materialdried over Na2SO4
  7. filtrationfiltered
  8. customevaporated

출처 및 근거

ORD 기록
ord-f9cb6d31854141cdbd18480a1b238b40
출처 데이터셋
uspto-grants-1996_05
특허 번호
US05514676

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