Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Adenine → 2-(6-Aminopurin-9-yl)ethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Adenine | HCID 190 | — |
| 반응물 | Toluene | HCID 1140 | — |
| 반응물 | Ethylene carbonate | HCID 7303 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-(6-Aminopurin-9-yl)ethanol | HCID 242652 | — |
반응 단계
Adenine (9.1 g), ethylene carbonate (6.0 g), and sodium hydroxide (0.14 g) in DMF (68 ml) were heated at reflux for 2 hr The solution was cooled to 0°, then 70 ml of toluene were added. After sitting for 2 hr at 0°, the precipitate was collected, rinsed with 100 ml of toluene, then cold ethanol, and dried to afford N9 -hydroxyethyladenine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05514798 |
| 출처 데이터셋 | uspto-grants-1996_05 |
| ORD ID | ord-bf4567b048f14c1da63f8477b7c5abad |
| 출처 메모 | uspto-grants-1996_05 |