Benzoic acid, 4-ethyl-, methyl ester → Methyl 4-(1-bromoethyl)benzoate
반응식
[CH2:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1)[CH3:2].[Br:13]N1C(=O)CCC1=O>C(Cl)(Cl)(Cl)Cl.C1C(C(OOOC(=O)C2C=CC=CC=2)=O)=CC=CC=1>[Br:13][CH:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1)[CH3:2]참가 물질
5
실험 절차
To a solution of methyl 4-ethylbenzoate (5.12 g) in carbon tetrachloride (50 ml) were added perbenzoic anhydride (0.20 g) and N-bromosuccinimide (6.07 g) in turn, and the mixture was heated and refluxed. After 30 minutes, the mixture was allowed to cool, and the precipitate was separated by filtration, and washed with carbon tetrachloride. The filtrate and the washings were combined, and concentrated under reduced pressure to give the title compound (8.28 g)
후처리
- temperaturethe mixture was heated
- temperaturerefluxed
- temperatureto cool
- customthe precipitate was separated by filtration
- washwashed with carbon tetrachloride
- concentrationconcentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-6752eb1d056948a78eb8c05cb67c60e2
- 출처 데이터셋
- uspto-grants-1996_05
- 특허 번호
- US05516777
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