Cinchomeronic acid → 1H,3H-furo(3,4-c)pyridine-1,3-dione

HRID 440350

반응식

HRID 440350 반응식
[N:1]1[CH:6]=[CH:5][C:4]([C:7]([OH:9])=O)=[C:3]([C:10]([OH:12])=[O:11])[CH:2]=1>C(OC(=O)C)(=O)C>[N:1]1[CH:6]=[CH:5][C:4]2[C:7]([O:12][C:10](=[O:11])[C:3]=2[CH:2]=1)=[O:9]

참가 물질

3

반응물 1

HCID 10273Cinchomeronic acid

생성물 1

HCID 2783981H,3H-furo(3,4-c)pyridine-1,3-dione수율 75.5%

시약·촉매·용매 1

HCID 7918Acetic Anhydride용매

실험 절차

A mixture of pyridine 3,4-dicarboxylic acid (15.0 g) and acetic anhydride (30 mL) is refluxed for two hours. The excess acetic anhydride is removed by distillation and the anhydride is collected and purified by sublimation (123° C. at 3 mm Hg) to yield pyridine 3,4-dicarboxylic acid anhydride as a white solid (10.1 g).

후처리

  1. temperatureis refluxed for two hours
  2. customThe excess acetic anhydride is removed by distillation
  3. customthe anhydride is collected
  4. custompurified by sublimation (123° C. at 3 mm Hg)

출처 및 근거

ORD 기록
ord-008e67ff95cd4f68ad40055b4987af1f
출처 데이터셋
uspto-grants-1996_05
특허 번호
US05519029

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