Undecanoic Acid → Undecanoyl chloride

HRID 440971

반응식

HRID 440971 반응식
[C:1]([OH:13])(=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].C(Cl)(=O)C([Cl:17])=O>C(Cl)Cl.CN(C)C=O>[C:1]([Cl:17])(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]

참가 물질

5

반응물 2

HCID 8180Undecanoic AcidHCID 65578Oxalyl chloride

생성물 1

HCID 87287Undecanoyl chloride수율 39.8%

시약·촉매·용매 2

HCID 6228Dimethylformamide촉매HCID 6344Dichloromethane용매

실험 절차

Under a nitrogen atmosphere, a solution of 5.0 grams (0.027 mole) of undecanoic acid in 75 mL of methylene chloride was stirred and 2.8 ml (0.032 mole) of oxalyl chloride and 5 drops of N,N-dimethylformamide were added. Upon completion of addition, the reaction mixture was stirred for about 16 hours, then it was concentrated under reduced pressure, yielding 2.2 grams of undecanoyl chloride.

후처리

  1. additionUpon completion of addition
  2. concentrationit was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-6e366cb4a7924555947d4f40ba8a8ff0
출처 데이터셋
uspto-grants-1996_05
특허 번호
US05521192

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