Glycine → Phenylalanine Serine

반응식

[NH2:1][C@H:2]([C:10]([OH:12])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[NH2:13][CH2:14][C:15]([OH:17])=[O:16]>>[NH2:1][C@H:2]([C:10]([OH:12])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[NH2:13][C@H:14]([C:15]([OH:17])=[O:16])[CH2:10][OH:11]

참가 물질

반응물 2

HCID 750Glycine

HCID 6140L-Phenylalanine

생성물 1

HCID 18611619Phenylalanine Serine

실험 절차

The formation of t-Boc--Phe--SerOH is obtained by the same process, but using 1.1 mmol of lyophilised hydrated serine in place of cysteine and 1 mmol of phenylalanine protected by t-Box and activated in place of glycine.

후처리

customThe formation of t-Boc--Phe--SerOH is obtained by the same process

출처 및 근거

ORD 기록: ord-bf52adeae66d476a983fab8d71fb9ecb
출처 데이터셋: uspto-grants-1988_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04725645

반응 노트

불러오는 중…