Benzyl Bromide → HCID 21418213, 화합물

HRID 441808

반응식

HRID 441808 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[N:8][CH:7]=[CH:6]2.[CH2:13]([Br:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>CC(C)=O.CCOCC>[Br-:20].[CH2:13]([N+:8]1[CH:7]=[CH:6][C:5]2[C:10](=[CH:11][CH:12]=[C:3]([O:2][CH3:1])[CH:4]=2)[CH:9]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

5

반응물 2

HCID 7498Benzyl BromideHCID 110409786-Methoxyisoquinoline

생성물 1

HCID 21418213HCID 21418213, 화합물

시약·촉매·용매 2

HCID 180Acetone용매HCID 3283Diethyl Ether용매

실험 절차

6-Methoxyisoquinoline (1.6 g) and benzyl bromide (2 ml) in acetone (75 ml) were heated under reflux for 1 hour. The mixture was diluted with ether and cooled to 0°. The solid was filtered off and recrystallised from methanol/ether, and had m.p. 155°-158°.

후처리

  1. temperatureunder reflux for 1 hour
  2. temperaturecooled to 0°
  3. filtrationThe solid was filtered off
  4. customrecrystallised from methanol/ether

출처 및 근거

ORD 기록
ord-a515023c47354e99bfa7c2376c17c423
출처 데이터셋
uspto-grants-1977_08
특허 번호
US04042697

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