Acetic Anhydride → HCID 21416538, 화합물

반응식

NC(C(O)CCCCC)C(O)=O.C(OC(=O)C)(=O)C.[C:20]([NH:23][CH:24]([CH:28]([OH:34])[CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[C:25](O)=[O:26])(=[O:22])[CH3:21].COC(=O)C(NC(=O)C)C(O)CCCCC.[H-].C([Al+]CC(C)C)C(C)C>CO>[C:20]([NH:23][CH:24]([CH:28]([OH:34])[CH2:29][CH2:30][CH2:31][CH2:32][CH3:33])[CH:25]=[O:26])(=[O:22])[CH3:21]

참가 물질

반응물 5

HCID 7918Acetic Anhydride

HCID 187908012-Amino-3-hydroxyoctanoic acid

HCID 21225700Diisobutylaluminumhydride

HCID 21416541HCID 21416541, 화합물

HCID 53991059HCID 53991059, 화합물

생성물 1

HCID 21416538HCID 21416538, 화합물

시약·촉매·용매 1

실험 절차

Protect the amino function in the 2-amino-3-hydroxy-octanoic acid by conversion thereof to an acetamido function by reaction with acetic anhydride, then esterify the resultant 2-acetamido-3-hydroxyoctanoic acid with methanol; reduce the resultant 2-acetamido-3-hydroxyoctanoic acid methyl ester with di-isobutylaluminum hydride according to known procedures to obtain 2-acetamido-3-hydroxyoctanal.

출처 및 근거

ORD 기록: ord-1a7b7a89240346628843ee1eecaeb263
출처 데이터셋: uspto-grants-1977_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04044123

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