Sodium borohydride → 4-Anilinocarbonylmethylamino-1-(4-phenyl-4-hydroxybutyl)-piperidine

반응식

[NH:1]([C:8]([CH2:10][NH:11][CH:12]1[CH2:17][CH2:16][N:15]([CH2:18][CH2:19][CH2:20][C:21]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[O:22])[CH2:14][CH2:13]1)=[O:9])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[BH4-].[Na+]>>[NH:1]([C:8]([CH2:10][NH:11][CH:12]1[CH2:13][CH2:14][N:15]([CH2:18][CH2:19][CH2:20][CH:21]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[OH:22])[CH2:16][CH2:17]1)=[O:9])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 4311764Sodium borohydride

HCID 21415057HCID 21415057, 화합물

생성물 1

HCID 214150584-Anilinocarbonylmethylamino-1-(4-phenyl-4-hydroxybutyl)-piperidine

실험 절차

4-Anilinocarbonylmethylamino-1-(4-phenyl-4-oxobutyl) piperidine may be reduced using sodium borohydride to give the title compound.

출처 및 근거

ORD 기록: ord-e398f27089914904b3b1d60c23da5ce9
출처 데이터셋: uspto-grants-1977_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04045566

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