Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazinecarboxaldehyde → 6-(3-Pyridinyl)-1,2,4-triazolo[4,3-b]pyridazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazinecarboxaldehyde | HCID 12229 | — |
| 반응물 | 3-Chloro-6-(pyridin-3-yl)pyridazine | HCID 16732435 | — |
| 용매 | 1-Butanol | HCID 263 | — |
| 생성물 | 6-(3-Pyridinyl)-1,2,4-triazolo[4,3-b]pyridazine | HCID 14287977 | — |
반응 단계
A mixture of 1.5 g. of 3-chloro-6-(3-pyridyl)pyridazine and 0.96 g. of formic acid hydrazide in 50 ml. of n-butyl alcohol is refluxed for 48 hours. The reaction mixture is concentrated, partitioned and crystallized as described in Example 1 to afford 1.0 g. of the product of the Example as a cream colored solid, m.p. 199°-200°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04260756 |
| 출처 데이터셋 | uspto-grants-1981_04 |
| ORD ID | ord-8179f5fda6934fe5921f263e191122e3 |
| 출처 메모 | uspto-grants-1981_04 |