1,3-Dichloroacetone → HCID 86736622, 화합물

HRID 444007노트

반응식

HRID 444007 반응식
[Cl:1][CH2:2][C:3]([CH2:5]Cl)=O.[CH2:7]([NH:11][C:12]([NH:14][C:15]([NH2:17])=[S:16])=[NH:13])[CH2:8][CH2:9][CH3:10]>CC(C)=O>[ClH:1].[CH2:7]([N:11]=[C:12]([NH2:13])[NH:14][C:15]1[S:16][CH:5]=[C:3]([CH2:2][Cl:1])[N:17]=1)[CH2:8][CH2:9][CH3:10]

참가 물질

4

반응물 2

HCID 107931,3-DichloroacetoneHCID 178449223HCID 178449223, 화합물

생성물 1

HCID 86736622HCID 86736622, 화합물

시약·촉매·용매 1

HCID 180Acetone용매2회

실험 절차

A solution of 1,3-dichloroacetone (3.02 g.) in acetone (10 ml.) was added to a stirred suspension of (N-n-butylamidino)thiourea (4.04 g.) in acetone (25 ml.) at room temperature. The resulting clear pale yellow solution was stirred for three days, then cooled in ice, and the precipitated solid filtered off and washed with acetone to give 2-(2-n-butylguanidino)-4-chloromethylthiazole hydrochloride.

후처리

  1. temperaturecooled in ice
  2. filtrationthe precipitated solid filtered off
  3. washwashed with acetone

출처 및 근거

ORD 기록
ord-84086ea8dd454f728c4a0af36eb519fc
출처 데이터셋
uspto-grants-1981_04
특허 번호
US04262126

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