Formamide → 2-Formamidotridecane

HRID 444247

반응식

HRID 444247 반응식
[CH2:1]([C:12]([CH3:14])=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].[CH:15]([NH2:17])=[O:16]>C(O)=O>[CH:15]([NH:17][CH:12]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[CH3:14])=[O:16]

참가 물질

4

반응물 2

HCID 713FormamideHCID 116222-Tridecanone

생성물 1

HCID 217010542-Formamidotridecane

시약·촉매·용매 1

HCID 284Formic Acid용매

반응 조건

온도
160 °C

실험 절차

70 g of methyl undecyl ketone are added to 250 ml of formamide. The mixture is heated, with constant stirring, to 160° C. Then 40 ml of formic acid are added dropwise in the course of 24 hours. The reaction mixture is cooled, poured on ice, extracted with ether and the ethereal extract is dried over Na2SO4. After distilling off the ether, the oily residue is distilled in vacuo, affording 60 g of 2-formamidotridecane. Boiling point: 145°-155° C./0.01.

후처리

  1. temperatureThe reaction mixture is cooled
  2. additionpoured on ice
  3. extractionextracted with ether
  4. extractionthe ethereal extract
  5. dry with materialis dried over Na2SO4
  6. distillationAfter distilling off the ether
  7. distillationthe oily residue is distilled in vacuo

출처 및 근거

ORD 기록
ord-6418589092854135addf7e409ec13f14
출처 데이터셋
uspto-grants-1981_04
특허 번호
US04263324

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