Cholesterol → 1,4,6-Cholestatrien-3-one

HRID 444409

반응식

HRID 444409 반응식
[CH3:1][CH:2]([CH2:4][CH2:5][CH2:6][C@H:7]([C@@H:9]1[C@:27]2([CH3:28])[C@H:12]([C@H:13]3[C@H:24]([CH2:25][CH2:26]2)[C@:22]2([CH3:23])[C:16]([CH2:17][C@H:18]([CH2:20][CH2:21]2)[OH:19])=[CH:15][CH2:14]3)[CH2:11][CH2:10]1)[CH3:8])[CH3:3].ClC1C(=O)C(C#N)=C(C#N)C(=O)C=1Cl>O1CCOCC1>[CH3:3][CH:2]([CH2:4][CH2:5][CH2:6][C@H:7]([C@@H:9]1[C@:27]2([CH3:28])[C@H:12]([C@H:13]3[C@H:24]([CH2:25][CH2:26]2)[C@:22]2([CH3:23])[C:16](=[CH:17][C:18](=[O:19])[CH:20]=[CH:21]2)[CH:15]=[CH:14]3)[CH2:11][CH2:10]1)[CH3:8])[CH3:1]

참가 물질

4

반응물 2

HCID 5997CholesterolHCID 67752,3-Dichloro-5,6-dicyano-1,4-benzoquinone

생성물 1

HCID 1073901,4,6-Cholestatrien-3-one수율 56%

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

1,4,6-cholestatrien-3 one was prepared in 56% yield from cholesterol, 2,3-dichloro-5,6-dicyano-1,4-benzoquinone and dioxane by the procedure of A. B. Turner J. Chem. Soc. C, 2568 (1968).

출처 및 근거

ORD 기록
ord-783a3b8375f74c19a65838b24427a38f
출처 데이터셋
uspto-grants-1981_04
특허 번호
US04264512

연결된 노트

불러오는 중…