Lithium Hydroxide → HCID 2800115, 화합물

HRID 444460노트

반응식

HRID 444460 반응식
Cl[C:2]1[N:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=1.[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([SH:18])=[CH:14][CH:13]=1.[OH-].[Li+]>CN(C=O)C>[Cl:11][C:12]1[CH:17]=[CH:16][C:15]([S:18][C:2]2[N:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=2)=[CH:14][CH:13]=1

참가 물질

5

반응물 3

HCID 3939Lithium HydroxideHCID 7815p-ChlorothiophenolHCID 783082-Chloro-5-nitropyridine

생성물 1

HCID 2800115HCID 2800115, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

6-Chloro-3-nitropyridine (4.0 grams) and 4-chlorothiophenol (3.7 grams) were mixed in 100 ml. of dry DMF and lithium hydroxide (1.2 grams) added portionwise. After the reaction mixture had stirred for about 5 minutes, it darkened and became warm. It was allowed to stir with a drying tube for 4 hours, poured over ice water and the product separated by filtration. It was crystallized from ethyl acetate-ethanol, yield: 5.0 grams, m.p. 134°-136° C.

후처리

  1. temperaturebecame warm
  2. stirringto stir with a drying tube for 4 hours
  3. customthe product separated by filtration
  4. customIt was crystallized from ethyl acetate-ethanol, yield: 5.0 grams, m.p. 134°-136° C.

출처 및 근거

ORD 기록
ord-57955474b9ae4295a26ab436bd0a52c1
출처 데이터셋
uspto-grants-1981_04
특허 번호
US04264605

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