4-Hydroxybenzaldehyde → Benzaldehyde, 4-(acetyloxy)-

HRID 446197

반응식

HRID 446197 반응식
[OH:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.[C:10](OC(=O)C)(=[O:12])[CH3:11]>N1C=CC=CC=1>[C:10]([O:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1)(=[O:12])[CH3:11]

참가 물질

4

반응물 2

HCID 1264-HydroxybenzaldehydeHCID 7918Acetic Anhydride

생성물 1

HCID 70144Benzaldehyde, 4-(acetyloxy)-수율 93%

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

To the solution of 4-hydroxybenzaldehyde (10.0 g, 81.9 mmol) in 150 ml of pyridine was added acetic anhydride (60 ml). The resultant mixture was stirred at room temperature for 2 hours. After removal of the solvent, the compound was purified by flash chromatography using heptane/methylene chloride/ethyl acetate (20/20/10) as eluent in a yield of 93%.

후처리

  1. customAfter removal of the solvent
  2. customthe compound was purified by flash chromatography

출처 및 근거

ORD 기록
ord-a3854bd679c14cadbdebfa4ffdf351e0
출처 데이터셋
uspto-grants-2013_07
특허 번호
US08476450B2

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