Sodium Hydroxide → 1-phenyl-1H-indazole-6-carboxylic acid

반응식

C[O:2][C:3]([C:5]1[CH:13]=[C:12]2[C:8]([CH:9]=[N:10][N:11]2[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[C:7](C2C=CC(C)=CN=2)[CH:6]=1)=[O:4].[OH-].[Na+]>>[C:14]1([N:11]2[C:12]3[C:8](=[CH:7][CH:6]=[C:5]([C:3]([OH:4])=[O:2])[CH:13]=3)[CH:9]=[N:10]2)[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

참가 물질

반응물 2

HCID 14798Sodium Hydroxide

HCID 596277764-(5-Methyl-pyridin-2-yl)-1-phenyl-1H-indazole-6-carboxylic acid methyl ester

생성물 1

HCID 866493201-phenyl-1H-indazole-6-carboxylic acid

실험 절차

4-(5-Methyl-pyridin-2-yl)-1-phenyl-1H-indazole-6-carboxylic acid methyl ester was treated with NaOH using the procedure of step 3 of Example 1 to afford 445-methyl-pyridin-2-yl)-1-phenyl-1H-indazole-6-carboxylic acid.

출처 및 근거

ORD 기록: ord-9882663063c54d338fa12eca733a5a9c
출처 데이터셋: uspto-grants-2013_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08476457B2

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