Hydrochloric Acid → HCID 178491370, 화합물
반응식
Cl.[CH3:2][O:3][C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][CH3:13])[C:5]=1[CH2:6][NH2:7].[N-:14]([C:17]#[N:18])[C:15]#[N:16].[Na+]>>[C:15]([NH:14][C:17]([NH:7][CH2:6][C:5]1[C:8]([O:12][CH3:13])=[CH:9][CH:10]=[CH:11][C:4]=1[O:3][CH3:2])=[NH:18])#[N:16]참가 물질
4
실험 절차
15 ml 2N hydrochloric acid were added to 5.0 g (29.9 mmol) 2,6-dimethoxybenzylamine and the aqueous phase was subsequently removed under vacuum. The residue was then dissolved in 50 ml 1-butanol and 2.66 g (29.9 mmol) of sodium dicyanamide were added. The reaction mixture was heated for 5.5 hours at reflux and stirred for 12 hours at room temperature. The precipitate formed was filtered off, was washed with diethylether; 6.81 g.
후처리
- customthe aqueous phase was subsequently removed under vacuum
- dissolutionThe residue was then dissolved in 50 ml 1-butanol
- temperatureThe reaction mixture was heated for 5.5 hours
- temperatureat reflux
- customThe precipitate formed
- filtrationwas filtered off
- washwas washed with diethylether
출처 및 근거
- ORD 기록
- ord-0740ffcdbd084f38a1576fed031345a4
- 출처 데이터셋
- uspto-grants-2013_07
- 특허 번호
- US08481576B2
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