Dichloromethane → HCID 57171531, 화합물

HRID 449118

반응식

HRID 449118 반응식
[CH2:1]([C:3]1[CH:4]=[C:5]([OH:10])[CH:6]=[CH:7][C:8]=1[Cl:9])[CH3:2].[C:11]1(B(O)O)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.C(Cl)Cl>>[Cl:9][C:8]1[CH:7]=[CH:6][C:5]([O:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:4][C:3]=1[CH2:1][CH3:2]

참가 물질

4

반응물 3

HCID 6344DichloromethaneHCID 66827Phenylboronic AcidHCID 842234-Chloro-3-ethylphenol

생성물 1

HCID 57171531HCID 57171531, 화합물

실험 절차

3-ethyl-4-chlorophenol (2.0 g, 0.013 mol), phenylboronic acid (4.7 g, 0.038 mol), TEA (11 mL, 0.077 mol), cupric acetate (4.2 g, 0.023 mol) and DCM (60 mL, 0.9 mol) were added to a 100 mL oven dried flask and the reaction was stirred at rt for 24 h. The solvent was then removed under reduced pressure and the resulting residue was purified by flash chromatography (5% EtOAc in Hexane).

후처리

  1. customdried flask
  2. customThe solvent was then removed under reduced pressure
  3. customthe resulting residue was purified by flash chromatography (5% EtOAc in Hexane)

출처 및 근거

ORD 기록
ord-468ee86025da4a8694d036ab3c535b72
출처 데이터셋
uspto-grants-2013_07
특허 번호
US08481733B2

연결된 노트

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