Isopropyl isocyanate → HCID 59496751, 화합물

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[N:1]([CH:4]([CH3:6])[CH3:5])=[C:2]=[O:3].Cl.[CH3:8][N:9]1[CH2:14][CH2:13][N:12]([C:15]2[CH:20]=[C:19]([C:21]3[CH:30]=[C:29]4[C:24]([CH2:25][CH2:26][NH:27][CH2:28]4)=[CH:23][CH:22]=3)[N:18]=[C:17]([NH2:31])[N:16]=2)[CH2:11][CH2:10]1>>[NH2:31][C:17]1[N:18]=[C:19]([C:21]2[CH:30]=[C:29]3[C:24]([CH2:25][CH2:26][N:27]([C:2]([NH:1][CH:4]([CH3:6])[CH3:5])=[O:3])[CH2:28]3)=[CH:23][CH:22]=2)[CH:20]=[C:15]([N:12]2[CH2:11][CH2:10][N:9]([CH3:8])[CH2:14][CH2:13]2)[N:16]=1

참가 물질

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HCID 61277Isopropyl isocyanate

HCID 675414894-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt

생성물 1

HCID 59496751HCID 59496751, 화합물

실험 절차

This compound was prepared from 2-isocyanatopropane and 4-(4-methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine HCl salt using procedures analogous to those for Example 5. Analytic LCMS (M+H)+: m/z=410.4.

출처 및 근거

ORD 기록: ord-3d3210c2dd964c5b9979341857cb2931
출처 데이터셋: uspto-grants-2013_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08481732B2

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