Hydrazine → Aminotetrahydrocyclopenta[b]indole

HRID 449824노트

반응식

HRID 449824 반응식
[CH2:1]1[C:12]2[CH:4]([N:5]=[C:6]3[C:11]=2[CH:10]=[CH:9][CH:8]=[CH:7]3)[CH2:3][CH2:2]1.[NH2:13]N.O.NN>>[NH2:13][CH:1]1[C:12]2[CH:4]([N:5]=[C:6]3[C:11]=2[CH:10]=[CH:9][CH:8]=[CH:7]3)[CH2:3][CH2:2]1

참가 물질

4

반응물 3

HCID 9321HydrazineHCID 24654Hydrazine hydrate (1:1)HCID 66869719Tetrahydrocyclopent(b)indole

생성물 1

HCID 66933239Aminotetrahydrocyclopenta[b]indole

실험 절차

Alternatively, in Scheme 2, Step G, the phthalimide group of the tetrahydrocyclopenta[b]indole of formula (8) is cleaved with hydrazine or hydrazine hydrate to provide an aminotetrahydrocyclopenta[b]indole of formula (9) as previously described in Step B. Subsequently, the resulting free amine is converted to the p-toluenesulfonic acid salt in ethanol.

출처 및 근거

ORD 기록
ord-e6ec40c164ec407883174806ceadbd88
출처 데이터셋
uspto-grants-2013_07
특허 번호
US08486943B2

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