Thionyl Chloride → 2,6-Dichloro-4-iodobenzoyl chloride

HRID 449917

반응식

HRID 449917 반응식
[Cl:1][C:2]1[CH:10]=[C:9]([I:11])[CH:8]=[C:7]([Cl:12])[C:3]=1[C:4](O)=[O:5].O=S(Cl)[Cl:15]>>[Cl:1][C:2]1[CH:10]=[C:9]([I:11])[CH:8]=[C:7]([Cl:12])[C:3]=1[C:4]([Cl:15])=[O:5]

참가 물질

3

반응물 2

HCID 24386Thionyl ChlorideHCID 513418772,6-Dichloro-4-iodobenzoic acid

생성물 1

HCID 866489582,6-Dichloro-4-iodobenzoyl chloride수율 100%

실험 절차

A solution of 2,6-dichloro-4-iodobenzoic acid (65 mg, 0.21 mmol) in SOCl2 (3 mL) was heated to reflux under nitrogen atmosphere overnight and then cooled to room temperature. The reaction was conentrated under reduced pressure to afford 2,6-dichloro-4-iodobenzoyl chloride (70 mg, 100% yield).

후처리

  1. temperatureto reflux under nitrogen atmosphere overnight

출처 및 근거

ORD 기록
ord-4d56422000ae457ca41ed97b75cb9c61
출처 데이터셋
uspto-grants-2013_07
특허 번호
US08486950B2

연결된 노트

불러오는 중…