Hydrazine hydrate (1:1) → N-{(1R,3S)-3-[(benzyloxy)methyl]cyclopentyl}-6-hydrazinyl-N-methylpyridine-3-sulfonamide
반응식
[CH2:1]([O:8][CH2:9][C@H:10]1[CH2:14][CH2:13][C@@H:12]([N:15]([CH3:26])[S:16]([C:19]2[CH:20]=[N:21][C:22](Cl)=[CH:23][CH:24]=2)(=[O:18])=[O:17])[CH2:11]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.O.[NH2:28][NH2:29]>>[CH2:1]([O:8][CH2:9][C@H:10]1[CH2:14][CH2:13][C@@H:12]([N:15]([CH3:26])[S:16]([C:19]2[CH:20]=[N:21][C:22]([NH:28][NH2:29])=[CH:23][CH:24]=2)(=[O:18])=[O:17])[CH2:11]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1참가 물질
3
실험 절차
According to process 5.2, starting with 0.58 g of N-{(1R,3S)-3-[(benzyloxy)methyl]-cyclopentyl}-6-chloro-N-methylpyridine-3-sulfonamide and 0.15 mL of hydrazine hydrate, 0.49 g of N-{(1R,3S)-3-[(benzyloxy)methyl]cyclopentyl}-6-hydrazinyl-N-methylpyridine-3-sulfonamide is obtained.
출처 및 근거
- ORD 기록
- ord-1bc3c03c73a441b1bbc03c4784f126cc
- 출처 데이터셋