HCID 86667286, 화합물 → HCID 86667285, 화합물

HRID 453324노트

반응식

HRID 453324 반응식
[CH3:1][O:2][C:3](=[O:29])/[CH:4]=[CH:5]/[C:6]1[CH:10]=[C:9]([CH3:11])[N:8]([CH:12]([O:20][CH2:21][C:22]2[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][CH:23]=2)[C:13]2[CH:18]=[C:17]([Cl:19])[CH:16]=[CH:15][CH:14]=2)[N:7]=1>C1COCC1.CO.[Pt]>[CH3:1][O:2][C:3](=[O:29])[CH2:4][CH2:5][C:6]1[CH:10]=[C:9]([CH3:11])[N:8]([CH:12]([O:20][CH2:21][C:22]2[CH:23]=[CH:24][C:25]([Cl:28])=[CH:26][CH:27]=2)[C:13]2[CH:18]=[C:17]([Cl:19])[CH:16]=[CH:15][CH:14]=2)[N:7]=1

참가 물질

5

반응물 1

HCID 86667286HCID 86667286, 화합물

생성물 1

HCID 86667285HCID 86667285, 화합물

시약·촉매·용매 3

HCID 23939Platinum촉매HCID 887Methanol용매HCID 8028Tetrahydrofuran용매

실험 절차

A suspension of unsaturated ester 6 (0.31 g, 0.65 mmol) and 5 Pt/C (0.01 g) in THF (6 mL) and MeOH (12 mL), previously purged with nitrogen, was stirred under a hydrogen atmosphere (balloon) at RT overnight. The platinum was removed by filtration through Hyflo and the filtrate was evaporated to dryness to afford the saturated ester 7, 0.31 g (99%).

후처리

  1. custompreviously purged with nitrogen
  2. customThe platinum was removed by filtration through Hyflo
  3. customthe filtrate was evaporated to dryness

출처 및 근거

ORD 기록
ord-e63128a57fbe4abbaad2a3d3daf7221a
출처 데이터셋
uspto-grants-2013_07
특허 번호
US08492424B2

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