Sodium Hydroxide → HCID 58508470, 화합물

HRID 454773노트

반응식

HRID 454773 반응식
[OH-].[Na+:2].[OH:3][C:4]1[CH:5]=[C:6]([C:10]2[CH:18]=[CH:17][C:13]([C:14]([OH:16])=[O:15])=[C:12]([NH:19][C:20]([C:22]3[CH:23]=[N:24][CH:25]=[C:26]([C:28]4[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=4)[CH:27]=3)=[O:21])[CH:11]=2)[CH:7]=[CH:8][CH:9]=1>C(O)C>[OH:3][C:4]1[CH:5]=[C:6]([C:10]2[CH:18]=[CH:17][C:13]([C:14]([O-:16])=[O:15])=[C:12]([NH:19][C:20]([C:22]3[CH:23]=[N:24][CH:25]=[C:26]([C:28]4[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=4)[CH:27]=3)=[O:21])[CH:11]=2)[CH:7]=[CH:8][CH:9]=1.[Na+:2]

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 58508471HCID 58508471, 화합물

생성물 1

HCID 58508470HCID 58508470, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Ethanol (4.0 mL) and a 1 mol/L aqueous solution of sodium hydroxide (0.17 mL) were sequentially added to the obtained 4-(3-hydroxyphenyl)-2-(5-phenylpyridine-3-carboxamido)benzoic acid (70 mg), followed by stirring at room temperature for 1 hour. The solvent was evaporated under reduced pressure, and ethanol and water were added to the obtained residue. The solid substance was collected by filtration to obtain 26 mg of sodium 4-(3-hydroxyphenyl)-2-(5-phenylpyridine-3-carboxamido)benzoate as a white solid.

후처리

  1. customThe solvent was evaporated under reduced pressure, and ethanol and water
  2. additionwere added to the obtained residue
  3. filtrationThe solid substance was collected by filtration

출처 및 근거

ORD 기록
ord-32d6ad06ef954c4fa475b9c67cc8f555
출처 데이터셋
uspto-grants-2013_07
특허 번호
US08492582B2

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