반응식
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:12][CH3:13])=[C:6]([CH2:8][C:9]([OH:11])=[O:10])[CH:7]=1.Cl.[CH3:15]O>>[CH3:15][O:10][C:9](=[O:11])[CH2:8][C:6]1[CH:7]=[C:2]([Br:1])[CH:3]=[CH:4][C:5]=1[O:12][CH3:13]참가 물질
4
반응 조건
- 온도
- 80 °C
실험 절차
To 5-bromo-2-methoxyphenylacetic acid (0.900 g, 3.7 mmol) in MeOH (20 mL) was added hydrogen chloride (4N in 1,4-dioxane; 4 mL), and the reaction was stirred at 80° C. for 6 hours. The mixture was then concentrated to dryness to give the title compound.
후처리
- concentrationThe mixture was then concentrated to dryness
출처 및 근거
- ORD 기록
- ord-6468b8e4aa80453a951593f3be6a0500
- 출처 데이터셋
- uspto-grants-2013_07
- 특허 번호
- US08497381B2
연결된 노트
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