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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 456241생성일: 2026년 10월 26일

2-Bromo-5-(trifluoromethyl)benzaldehyde → (6-Fluoro-2'-formyl-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

https://huagongshe.com/reaction/456241

반응식

참여 물질

역할이름HCID투입량
반응물2-Bromo-5-(trifluoromethyl)benzaldehydeHCID 7018047—
반응물Methyl [4-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetateHCID 46739456—
생성물(6-Fluoro-2'-formyl-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl esterHCID 86633169—

반응 단계

Prepared according to the procedure described in Example 25, Step 3, using the following starting materials: 2-bromo-5-trifluoromethyl-benzaldehyde and [4-fluoro-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid methyl ester; the isolated product was further purified by preparative HPLC.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08497381B2
출처 데이터셋uspto-grants-2013_07
ORD IDord-914b9f35f9da455596557ffce904cd50
출처 메모uspto-grants-2013_07