Sodium Hydroxide → (2S)-4'-{3-[4-(2-Carboxy-2-methoxy-ethyl)-2-methoxy-phenoxy]-propoxy}-biphenyl-4-carboxylic acid
반응식
C[O:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[CH:16]=[CH:15][C:14]([O:17][CH2:18][CH2:19][CH2:20][O:21][C:22]3[CH:27]=[CH:26][C:25]([CH2:28][C@H:29]([O:34][CH3:35])[C:30]([O:32]C)=[O:31])=[CH:24][C:23]=3[O:36][CH3:37])=[CH:13][CH:12]=2)=[CH:7][CH:6]=1)=[O:4].[OH-].[Na+].CO[2H]>>[C:30]([C@@H:29]([O:34][CH3:35])[CH2:28][C:25]1[CH:26]=[CH:27][C:22]([O:21][CH2:20][CH2:19][CH2:18][O:17][C:14]2[CH:13]=[CH:12][C:11]([C:8]3[CH:9]=[CH:10][C:5]([C:3]([OH:4])=[O:2])=[CH:6][CH:7]=3)=[CH:16][CH:15]=2)=[C:23]([O:36][CH3:37])[CH:24]=1)([OH:32])=[O:31]참가 물질
4
실험 절차
The title compound was prepared from 4′-{3-[2-methoxy-4-(2-methoxy-2-methoxycarbonyl-ethyl)-phenoxy]-propoxy}-biphenyl-4-carboxylic acid methyl ester (Step B) by standard hydrolysis procedure C (NaOH). 1H-NMR (MeOD, 300.15 MHz):